1959 Boys Varsity Football
Season:
| Sat, Sep 19 | Away vs Hamilton Taft | W 48-0 | 1-0 |
| Fri, Sep 25 | Home vs Dayton Colonel White | W 14-6 | 2-0 |
| Fri, Oct 02 | Home vs Withrow | W 42-6 | 3-0 |
| Fri, Oct 09 | Home vs Chillicothe | W 42-0 | 4-0 |
| Fri, Oct 16 | Home vs Alliance | W 14-8 | 5-0 |
| Sat, Oct 24 | Away vs Steubenville Central Catholic | L 8-20 | 5-1 |
| Sun, Nov 01 | Away vs Roger Bacon | W 8-6 | 6-1 / Played at Corcoran Field- Xavier University |
| Sun, Nov 08 | Home vs St. Xavier | W 14-6 | 7-1 |
| Sun, Nov 15 | Home vs Purcell | L 14-20 | 7-2 |
| Thu, Nov 26 | Home vs Western Hills | W 12-0 | 8-2 / Thanksgiving Day Game |