1961 Boys Varsity Football
Season:
| Fri, Sep 08 | Away vs Louisville St. Xavier | T 7-7 | 0-0-1 |
| Fri, Sep 15 | Home vs Chillicothe | W 37-6 | 1-0-1 |
| Fri, Sep 22 | Home vs McNicholas | W 20-6 | 2-0-1 |
| Fri, Sep 29 | Home vs Withrow | W 36-12 | 3-0-1 |
| Fri, Oct 06 | Away vs Chaminade | W 16-0 | 4-0-1 / Played at Welcome Stadium (UD) |
| Fri, Oct 20 | Home vs Dayton Dunbar | W 36-6 | 5-0-1 |
| Sun, Oct 29 | Away vs Purcell | W 34-20 | 6-0-1 / Played at Corcoran Field- Xavier University |
| Sun, Nov 05 | Away vs St. Xavier | W 6-0 | 7-0-1 / Played at Lockland |
| Sun, Nov 12 | Home vs Roger Bacon | L 6-18 | 7-1-1 |
| Thu, Nov 23 | Home vs Western Hills | W 28-0 | 8-1-1 / Played at Trechter Memorial Stadium/ Thanksgiving Day Game |